Owen County won 30-18 last year in Owenton.
In the last ten meetings between the two schools, the series is even at 5-5.
The Panthers are coached by Lee Downey who is in his second season.
Carroll County finished the season 5-6 in 2015.
The Panthers have not enjoyed a winning season since 2012 when they finished 7-4.
In other district action on Friday night, Walton-Verona (5-3, 3-0) hosts Trimble County (1-7, 0-2). Gallatin County has a bye.